A REVIEW OF PRO33

max in WT synaptoneurosomes, suggesting that Src signaling could be downregulated in KI synapses. Alternatively, our ability to rescue SERT functionality in KI midbrain synaptoneurosomes via the inhibition of FAK suggests elevated FAK signaling downstream in the Pro32Pro33 mutant, as confirmed by greater pFAK localization in 5-HT synapses. Our info